Experimental drug shows promise for treatment of postpartum depression

An experimental drug touted as a breakthrough for treating severe postpartum depression is showing some promising results in a small clinical trial. Sage Therapeutics (SAGE), based in Cambridge, Mass., reported on Tuesday that 7 of the 10 women who took the drug in the trial experienced significant improvement in their depression within 60 hours of … Read more

Ketamine Infusion Improves Abstinence in Cocaine-Dependent Patients

Ketamine infusion, combined with mindfulness-based behavioral changes, has been shown to improve various aspects of treatment outcomes among rehabilitating cocaine-dependent individuals.   The new findings from a randomized clinical trial show just a single infusion of the highly potent—yet controversial—NMDA receptor agonist is associated with significant patient improvements in cocaine abstinence at the trial’s end. Investigators—led by … Read more

Single, Repeated, and Maintenance Ketamine Infusions for Treatment-Resistant Depression: A Randomized Controlled Trial

  Abstract Objective: Subanesthetic ketamine doses have been shown to have rapid yet transient antidepressant effects in patients with treatment-resistant depression, which may be prolonged by repeated administration. The purpose of this study was to evaluate the antidepressant effects of a single ketamine infusion, a series of repeated ketamine infusions, and prolongation of response with … Read more

What Does The Mental Effect Of Ketamine Feel Like?

It’s not unusual for individuals who haven’t experienced Ketamine treatments before to feel nervous, much like any other initial medical procedure. There may be questions, worries, and uncertainties regarding the potential variations in experiences. These feelings are completely legitimate since, similar to any treatment, Ketamine can yield diverse results due to factors such as dosage … Read more

Guidelines for Use of IV Ketamine Infusions for Acute Pain Management Released

  The American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists have released consensus guidelines on the use of intravenous (IV) ketamine for the management of acute pain. “The use of ketamine for chronic pain has skyrocketed, and because it is an off-label use of a … Read more

An Effective Anxiety Treatment that You Haven’t Tried

  Everyone experiences occasional feelings of anxiety at some point in their lives. For example, you might feel anxious before taking a test, while making an important decision such as buying a new car or new home, or when you are faced with a particularly challenging project at work. However, for anyone with an anxiety … Read more

Population scale data reveals the antidepressant effects of ketamine

Abstract Current therapeutic approaches to depression fail for millions of patients due to lag in clinical response and non-adherence. Here we provide new support for the antidepressant effect of an anesthetic drug, ketamine, by Inverse-Frequency Analysis of eight million reports from the FDA Adverse Effect Reporting System. The results of the examination of population scale … Read more

Using Ketamine to Treat Post-Traumatic Stress Disorder in Service Members

For veterans, PTSD is an extremely common yet insufficiently treated problem. The Department of Veterans Affairs reports that about 21 veterans (including active duty servicemen, guards, and other military officials) commit suicide every single day. Ketamine has also been shown to help greatly with post-traumatic stress disorder. Roughly 7 out of 10 people have experienced … Read more

Ketamine: A New Way to Treat Teen Depression

Treatment shows promise where other antidepressants fail. Anxiety, depression and suicide are on the rise among American youth. But ketamine — a drug historically used as a surgical anesthetic — is showing promise as a treatment that can succeed where other antidepressant medications have failed. The need for help is dire. A 2019 Pew report said 70 percent of teenagers report … Read more

Why Are Suicide Rates Rising?

  Humanity needs to have an uncomfortable conversation about suicide. It’s a growing problem in the West and one that we don’t give nearly enough attention. Around 800,000 people kill themselves every year, according to the World Health Organization. After car accidents, it’s the leading cause of death for people between ages 15 and 29. … Read more

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